The Reversal of Cognitive Decline (ReCODE) Protocol was developed by Dr. Dale Bredesen after more than three decades of research in neurodegeneration. The protocol is designed to help prevent the onset of Alzheimer’s, but also to alleviate symptoms in patients who already have the condition.
You might be skeptical of these claims. Most health professionals you’ve talked with have said that Alzheimer’s cannot be prevented or treated effectively. However, ReCODE has worked for many people and I’ll show you why. But first, let’s take a quick look at how ReCODE came to be.
Alzheimer’s: Going Against the Grain
The first step to effectively treating or curing a disease is understanding it. Since the early 1980’s, scientists have based clinical trials on the amyloid hypothesis. Amyloid is a sticky protein fragment that can build up in the brain and disrupt communication between brain cells, essentially acting like roadblocks between neurons, thereby stopping the “traffic” of information.
Experts concluded that Alzheimer’s disease was the result of these plaques accumulating in the brain. Therefore, the natural conclusion was that destroying these plaques would be an effective treatment for Alzheimer’s. It might even prevent it.
Unfortunately, over 400 clinical trials aimed at developing a drug to destroy the amyloid plaques, or stop its accumulation, have failed. In some cases, the drugs worked as intended.
However, the problem is the destruction of these plaques doesn’t improve symptoms in people already suffering from Alzheimer’s. Blocking the enzyme to prevent the formation of the plaques doesn’t prevent the onset of the disease, either. In fact, in some cases, instead of showing improvement, patients actually got worse.
Yet, scientists continue to work on developing drugs based on this theory, which is why billions of dollars have been spent and hundreds of drugs have been created, all for naught. None of them work.
Over the last 30 years, Dr. Bredesen and his colleagues, have made some fascinating discoveries that are changing the medical world’s view of Alzheimer’s.
The Brain Makes Amyloid for Protection
You read that right. The accumulation of amyloid plaque in the brain is a natural protective response. All brains make amyloid and all brains have a cleaning process that clears it out
In Alzheimer’s disease, this process becomes overwhelmed by the amount of amyloid being produced, impairing the ability of the brain to clear it out. Therefore, it’s imperative to discover why the brain is making so much amyloid in order to control it. A drug that destroys amyloid, but doesn’t address the cause of it, is destined to fail.
In other words, the condition develops as a result of the brain trying to protect itself. It’s like when you get stung by a mosquito. The area swells, reddens, and itches – in some cases, it even becomes hot – as your body sends everything it has to fight off the infection caused by the bite. It’s a protective response.
In the case of Alzheimer’s, the brain is over-producing amyloid and/or downsizing in an attempt to protect itself. The natural process is overwhelmed.
However, this is just a symptom. The real question that needs to be answered is – what’s causing this? The answer varies between individuals but includes:
suboptimal levels of nutrients, hormones and neurotransmitters
exposure to toxic elements
infections and viruses.
The Basic Principle of the ReCODE Protocol
The ReCODE Protocol relies on a very simple principle: find and eliminate the contributing factors for each individual.
While the core principle of ReCODE is relatively simple, the methodology is more complicated. There are so many triggers to account for, and they differ from one person to the next. This means a monotherapy – one drug to zap one feature of the disease - doesn’t work.
To explain his findings, Dr. Bredesen compares having Alzheimer's disease to a roof with 36 holes. To fix a leaky roof, you have to repair all the holes. Repairing one or two holes won't solve the problem. With Alzheimer's, a drug may help repair one or two holes, but what about the rest of them?
All the contributors need to be found and repaired in each person to control the symptoms. This can also be accomplished before symptoms appear, which helps to make prevention possible.
The testing and subsequent lifestyle changes, supplements, and very few pharmaceutical interventions that form the basis of the ReCODE program address multiple contributors to the disease.
These include metabolic issues, hormonal imbalances, toxicity, poor gut health and microbial balance, nutritional deficiencies, and genetic factors. Improvement is dependent upon finding the underlying contributors along with an individual's implementation of the personalized program.
The ReCODE Protocol: Evaluating Your Risk Factors
The best way to prevent or reverse cognitive decline is to evaluate where you stand by going through what Dr. Bredesen calls a cognoscopy.
A cognoscopy consists of a series of tests designed to determine which factors and triggers pose a risk to you. Once you know what and where the problem is, you are in a far better position to fix it.
The key is to conduct the evaluation as soon as possible, preferably before you have any symptoms of cognitive decline. The underlying contributors can be found early because the process begins before symptoms appear. In fact, Dr. Bredesen recommends a cognoscopy for everyone at age 45.
Five sub-types of Alzheimer’s have been identified by Dr. Bredesen according to their contributors. The test results help to determine which sub-type of Alzheimer’s you may have or be trending toward. Most people will have a combination of types. Nutrient deficiencies, inflammation, oxidative stress and insulin resistance are common in each type.
Inflammatory (Hot): Many things can cause inflammation (e.g., infections, viruses, trauma, oxidative stress, poor nutrition, and insulin resistance).
Atrophic (Cold): Loss of hormonal and nutrient support which happens with age, poor diet, lack of exercise, hysterectomy (especially under the age of 50), and illness. The essential hormones and nutrients include estradiol, testosterone, pregnenolone, progesterone, cortisol, DHEA-S, vitamin D, choline, B12, B6, folate, thyroid hormone, and insulin, to name a few.
Glyco-toxic (Sweet): Considered type 1.5, it's a combination of the inflammatory and atrophic types, and it's common among people with Type 2 diabetes.
Toxic (Vile): This type is caused by infections and toxins that cause inflammation, immune system issues, and cellular dysfunction leading to cognitive decline. It can be due to mold illness, a virus, bacterial infection, chemicals, and heavy metal toxicity like mercury from dental amalgams.
Vascular (Pale): In this type, the blood vessels are damaged, and this can be caused by high blood sugar, high homocysteine, high lipoprotein, inflammation, low testosterone, estradiol, and progesterone. The vascular type could be a part of types 1, 2, and 3.
Traumatic (Dazed): Head trauma can cause brain inflammation, nerve cell dysfunction, and declining cognitive function. It's common in athletes who sustain multiple concussions.
If you or someone you love is at the point of seeing a doctor, don't accept a one-size-fits-all diagnosis. There are multiple imbalances to be found and corrected within each individual that neurological testing alone will not uncover. They can be found, and if found before symptoms appear, or progress too far, optimizing them can lead to the prevention, reversal or better management of the disease.
This preventive and restorative approach is a functional approach that scientifically and systematically seeks to bring your body and brain back into balance and, with that, back into health.
The good news is that you don’t have to do everything on your own and you can get started with crucial lifestyle adjustments immediately. I provide group support through a private Facebook group,where you can interact with and learn from me, but also other people dealing with the same issues as you.
Alternatively, if you need a little more personalized help, you can book a call with me. We’ll discuss your current situation and what your next steps should be, thereby eliminating any guesswork and associated concerns.